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It is a stimulant medication that inhibits dopamine reuptake with more efficacy than its near relative, methylphenidate. It is structurally identical to methylphenidate, with the addition of a fluorine atom to the phenyl ring at position 4. This minor alteration in chemical structure has a substantial effect on the pharmacology and efficacy of the drug.
Several studies have evaluated 4-FMPH’s potential as an anti-cocaine drug. In one such trial, an ED50 of 0.26 mg/kg and a relative potency of 3.33 relative to methylphenidate were recorded. Nevertheless, despite its potential usefulness, 4-FMPH remains an aggressive chemical due to its propensity for misuse and the lack of extensive study into its safety and toxicity.
It is a potent dopamine reuptake inhibitor, which raises dopamine levels in the brain. Dopamine is an essential neurotransmitter for controlling mood, motivation, and focus. Raising dopamine levels, 4-FMPH provides heightened alertness, concentration, and motivation.
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